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Nature 594 , 594598 (2021)

While these medications may offer meaningful support for some patients, they are intended for a specific subset of individuals whose medical history, nutritional status, and recovery needs align with this approach

These include a 24-hour liquid-only diet before the procedure, point-of-care gastric ultrasound immediately before anesthesia when available, adjustment of the anesthesia plan to reduce aspiration risk, and delaying elective procedures when risk is expected to decrease, such as after the dose-escalation phase or resolution of gastrointestinal symptoms

Regulatory and Legal Challenges The evolving regulatory landscape creates ongoing challenges for healthcare providers and patients

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